表观遗传研究-康成生物丨数谱生物

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        1. 表观遗传研究

          国内学者使用康成表观表观遗传芯片6282018.cc威尼斯网址发表的6282018.cc威尼斯手机版

          The LINK-A lncRNA interacts with PtdIns (3, 4, 5) P3 to hyperactivate AKT and confer resistance to AKT inhibitors. Lin A, et al. Nature Cell Biology, 2017 
          A novel lncRNA GClnc1 promotes gastric carcinogenesis and may act as a modular scaffold of WDR5 and KAT2A complexes to specify the histone modification pattern. Sun T T, et al. Cancer discovery, 2016

          Integrative Transcriptome Analyses of Metabolic Responses in Mice Define Pivotal LncRNA Metabolic Regulators.Yang L, et al.  Cell Metabolism, 2016.

          Differential transcriptome expression in human nucleus accumbens as a function of loneliness. Canli T, et al. Molecular Psychiatry, 2016

          Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia. Nat Genet. 2011
          CRL4B Catalyzes H2AK119 Monoubiquitination and Coordinates with PRC2 to Promote Tumorigenesis. Cancer Cell. 2012

          Hypoxia Inducible Factor 2 Alpha Inhibits Hepatocellular Carcinoma Growth Through the Transcription Factor Dimerization Partner 3/ E2F Transcription Factor 1–Dependent Apoptotic Pathway. HEPATOLOGY. 2013

          Menin promotes hepatocellular carcinogenesis and epigenetically up-regulates Yap1 transcription. PNAS. 2013

          Prognostic significance of 2-hydroxyglutarate levels in acute myeloid leukemia in China. PNAS. 2013

          The N-terminus of histone H3 is required for de novo DNA methylation in chromatin. Proc Natl Acad Sci U S A. 2009


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